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Organocatalytic, enantioselective synthesis of benzoxaboroles via Wittig/oxa-Michael reaction Cascade of α-formyl boronic acids

An unprecedented enantioselective synthesis of 3-substituted benzoxaboroles has been developed. An in situ generated ortho-boronic acid containing chalcone provides the chiral benzoxaboroles via an asymmetric oxa-Michael addition of hydroxyl group attached to the boronic acid triggered by the cincho...

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Publicat a:Chem Sci
Autors principals: Hazra, Gurupada, Maity, Sanjay, Bhowmick, Sudipto, Ghorai, Prasanta
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380879/
https://ncbi.nlm.nih.gov/pubmed/28451370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc04522g
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