Interactions between Type 1 Interferons and the Th17 Response in Tuberculosis: Lessons Learned from Autoimmune Diseases

The classical paradigm of tuberculosis (TB) immunity, with a central protective role for Th1 responses and IFN-γ-stimulated cellular responses, has been challenged by unsatisfactory results of vaccine strategies aimed at enhancing Th1 immunity. Moreover, preclinical TB models have shown that increas...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Mourik, Bas C., Lubberts, Erik, de Steenwinkel, Jurriaan E. M., Ottenhoff, Tom H. M., Leenen, Pieter J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380685/
https://ncbi.nlm.nih.gov/pubmed/28424682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00294
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