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Age-related spontaneous lacrimal keratoconjunctivitis is accompanied by dysfunctional T regulatory cells

In both humans and animal models the development of Sjögren syndrome (SS) and non-SS keratoconjunctivitis sicca (KCS) increases with age. Here, we investigated the ocular surface and lacrimal gland phenotype of NOD.B10.H2(b) mice at 7–14, 45–50, and 96–100 weeks. Aged mice develop increased corneal...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mucosal Immunol
Egile Nagusiak: Coursey, Terry G., Bian, Fang, Zaheer, Mahira, Pflugfelder, Stephen C., Volpe, Eugene A., de Paiva, Cintia S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380589/
https://ncbi.nlm.nih.gov/pubmed/27706128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2016.83
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