Llwytho...
Adaptive Reprogramming of De Novo Pyrimidine Synthesis is a Metabolic Vulnerability in Triple-Negative Breast Cancer
Chemotherapy resistance is a major barrier to the treatment of triple-negative breast cancer and strategies to circumvent resistance are required. Using in vitro and in vivo metabolic profiling of triple-negative breast cancer cells, we show that an increase in the abundance of pyrimidine nucleotide...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Cancer Discov |
|---|---|
| Prif Awduron: | , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2017
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5380483/ https://ncbi.nlm.nih.gov/pubmed/28255083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-16-0611 |
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