Frontline Science: HIV infection of Kupffer cells results in an amplified proinflammatory response to LPS

End-stage liver disease is a common cause of non-AIDS-related mortality in HIV(+) patients, despite effective anti-retroviral therapies (ARTs). HIV-1 infection causes gut CD4 depletion and is thought to contribute to increased gut permeability, bacterial translocation, and immune activation. Microbi...

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Опубликовано в: :J Leukoc Biol
Главные авторы: Mosoian, Arevik, Zhang, Lumin, Hong, Feng, Cunyat, Francesc, Rahman, Adeeb, Bhalla, Riti, Panchal, Ankur, Saiman, Yedidya, Fiel, M. Isabel, Florman, Sander, Roayaie, Sasan, Schwartz, Myron, Branch, Andrea, Stevenson, Mario, Bansal, Meena B.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Leukocyte Biology 2017
Предметы:
Spotlight on Leading Edge Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380374/
https://ncbi.nlm.nih.gov/pubmed/27986871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3HI0516-242R
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