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Enzyme-Instructed Assembly and Disassembly Processes for Targeting Downregulation in Cancer Cells

[Image: see text] Cancer cells differ from normal cells in both gain of functions (i.e., upregulation) and loss of functions (i.e., downregulation). While it is common to suppress gain of function for chemotherapy, it remains challenging to target downregulation in cancer cells. Here we show the com...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Feng, Zhaoqianqi, Wang, Huaimin, Zhou, Rong, Li, Jie, Xu, Bing
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380121/
https://ncbi.nlm.nih.gov/pubmed/28257192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b00070
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