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Steady-state EB cap size fluctuations are determined by stochastic microtubule growth and maturation

Growing microtubules are protected from depolymerization by the presence of a GTP or GDP/Pi cap. End-binding proteins of the EB1 family bind to the stabilizing cap, allowing monitoring of its size in real time. The cap size has been shown to correlate with instantaneous microtubule stability. Here w...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Rickman, Jamie, Duellberg, Christian, Cade, Nicholas I., Griffin, Lewis D., Surrey, Thomas
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380103/
https://ncbi.nlm.nih.gov/pubmed/28280102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620274114
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