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Host immunity to Plasmodium falciparum and the assessment of emerging artemisinin resistance in a multinational cohort

Artemisinin-resistant falciparum malaria, defined by a slow-clearance phenotype and the presence of kelch13 mutants, has emerged in the Greater Mekong Subregion. Naturally acquired immunity to malaria clears parasites independent of antimalarial drugs. We hypothesized that between- and within-popula...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Ataide, Ricardo, Ashley, Elizabeth A., Powell, Rosanna, Chan, Jo-Anne, Malloy, Michael J., O’Flaherty, Katherine, Takashima, Eizo, Langer, Christine, Tsuboi, Takafumi, Dondorp, Arjen M., Day, Nicholas P., Dhorda, Mehul, Fairhurst, Rick M., Lim, Pharath, Amaratunga, Chanaki, Pukrittayakamee, Sasithon, Hien, Tran Tinh, Htut, Ye, Mayxay, Mayfong, Faiz, M. Abul, Beeson, James G., Nosten, Francois, Simpson, Julie A., White, Nicholas J., Fowkes, Freya J. I.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380044/
https://ncbi.nlm.nih.gov/pubmed/28289193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1615875114
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