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Receptor Mincle promotes skin allergies and is capable of recognizing cholesterol sulfate

Sterile (noninfected) inflammation underlies the pathogenesis of many widespread diseases, such as allergies and autoimmune diseases. The evolutionarily conserved innate immune system is considered to play a key role in tissue injury recognition and the subsequent development of sterile inflammation...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Kostarnoy, Alexey V., Gancheva, Petya G., Lepenies, Bernd, Tukhvatulin, Amir I., Dzharullaeva, Alina S., Polyakov, Nikita B., Grumov, Daniil A., Egorova, Daria A., Kulibin, Andrey Y., Bobrov, Maxim A., Malolina, Ekaterina A., Zykin, Pavel A., Soloviev, Andrey I., Riabenko, Evgeniy, Maltseva, Diana V., Sakharov, Dmitry A., Tonevitsky, Alexander G., Verkhovskaya, Lyudmila V., Logunov, Denis Y., Naroditsky, Boris S., Gintsburg, Alexander L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380039/
https://ncbi.nlm.nih.gov/pubmed/28292894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1611665114
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