Receptor Mincle promotes skin allergies and is capable of recognizing cholesterol sulfate

Sterile (noninfected) inflammation underlies the pathogenesis of many widespread diseases, such as allergies and autoimmune diseases. The evolutionarily conserved innate immune system is considered to play a key role in tissue injury recognition and the subsequent development of sterile inflammation...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Kostarnoy, Alexey V., Gancheva, Petya G., Lepenies, Bernd, Tukhvatulin, Amir I., Dzharullaeva, Alina S., Polyakov, Nikita B., Grumov, Daniil A., Egorova, Daria A., Kulibin, Andrey Y., Bobrov, Maxim A., Malolina, Ekaterina A., Zykin, Pavel A., Soloviev, Andrey I., Riabenko, Evgeniy, Maltseva, Diana V., Sakharov, Dmitry A., Tonevitsky, Alexander G., Verkhovskaya, Lyudmila V., Logunov, Denis Y., Naroditsky, Boris S., Gintsburg, Alexander L.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2017
Предметы:
PNAS Plus
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380039/
https://ncbi.nlm.nih.gov/pubmed/28292894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1611665114
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