Receptor Mincle promotes skin allergies and is capable of recognizing cholesterol sulfate

Sterile (noninfected) inflammation underlies the pathogenesis of many widespread diseases, such as allergies and autoimmune diseases. The evolutionarily conserved innate immune system is considered to play a key role in tissue injury recognition and the subsequent development of sterile inflammation...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Kostarnoy, Alexey V., Gancheva, Petya G., Lepenies, Bernd, Tukhvatulin, Amir I., Dzharullaeva, Alina S., Polyakov, Nikita B., Grumov, Daniil A., Egorova, Daria A., Kulibin, Andrey Y., Bobrov, Maxim A., Malolina, Ekaterina A., Zykin, Pavel A., Soloviev, Andrey I., Riabenko, Evgeniy, Maltseva, Diana V., Sakharov, Dmitry A., Tonevitsky, Alexander G., Verkhovskaya, Lyudmila V., Logunov, Denis Y., Naroditsky, Boris S., Gintsburg, Alexander L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380039/
https://ncbi.nlm.nih.gov/pubmed/28292894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1611665114
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