Eosinophil-derived IL-4 drives progression of myocarditis to inflammatory dilated cardiomyopathy

Inflammatory dilated cardiomyopathy (DCMi) is a major cause of heart failure in children and young adults. DCMi develops in up to 30% of myocarditis patients, but the mechanisms involved in disease progression are poorly understood. Patients with eosinophilia frequently develop cardiomyopathies. In...

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Vydáno v:J Exp Med
Hlavní autoři: Diny, Nicola L., Baldeviano, G. Christian, Talor, Monica V., Barin, Jobert G., Ong, SuFey, Bedja, Djahida, Hays, Allison G., Gilotra, Nisha A., Coppens, Isabelle, Rose, Noel R., Čiháková, Daniela
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2017
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379983/
https://ncbi.nlm.nih.gov/pubmed/28302646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161702
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