Structure of the RZZ complex and molecular basis of its interaction with Spindly

Kinetochores are macromolecular assemblies that connect chromosomes to spindle microtubules (MTs) during mitosis. The metazoan-specific ≈800-kD ROD–Zwilch–ZW10 (RZZ) complex builds a fibrous corona that assembles on mitotic kinetochores before MT attachment to promote chromosome alignment and robust...

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Publicado en:J Cell Biol
Main Authors: Mosalaganti, Shyamal, Keller, Jenny, Altenfeld, Anika, Winzker, Michael, Rombaut, Pascaline, Saur, Michael, Petrovic, Arsen, Wehenkel, Annemarie, Wohlgemuth, Sabine, Müller, Franziska, Maffini, Stefano, Bange, Tanja, Herzog, Franz, Waldmann, Herbert, Raunser, Stefan, Musacchio, Andrea
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2017
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379955/
https://ncbi.nlm.nih.gov/pubmed/28320825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201611060
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