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Complex assembly, crystallization and preliminary X-ray crystallographic analysis of the human Rod–Zwilch–ZW10 (RZZ) complex

The spindle-assembly checkpoint (SAC) monitors kinetochore–microtubule attachment during mitosis. In metazoans, the three-subunit Rod–Zwilch–ZW10 (RZZ) complex is a crucial SAC component that interacts with additional SAC-activating and SAC-silencing components, including the Mad1–Mad2 complex and c...

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Опубликовано в: :Acta Crystallogr F Struct Biol Commun
Главные авторы: Altenfeld, Anika, Wohlgemuth, Sabine, Wehenkel, Annemarie, Vetter, Ingrid R., Musacchio, Andrea
Формат: Artigo
Язык:Inglês
Опубликовано: International Union of Crystallography 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388180/
https://ncbi.nlm.nih.gov/pubmed/25849506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X15004343
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