Evolutionary insights into T-type Ca(2+) channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue

Four-domain voltage-gated Ca(2+) (Ca(v)) channels play fundamental roles in the nervous system, but little is known about when or how their unique properties and cellular roles evolved. Of the three types of metazoan Ca(v) channels, Ca(v)1 (L-type), Ca(v)2 (P/Q-, N- and R-type) and Ca(v)3 (T-type),...

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Vydáno v:J Gen Physiol
Hlavní autoři: Smith, Carolyn L., Abdallah, Salsabil, Wong, Yuen Yan, Le, Phuong, Harracksingh, Alicia N., Artinian, Liana, Tamvacakis, Arianna N., Rehder, Vincent, Reese, Thomas S., Senatore, Adriano
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2017
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379919/
https://ncbi.nlm.nih.gov/pubmed/28330839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201611683
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