Evolutionary insights into T-type Ca(2+) channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue

Four-domain voltage-gated Ca(2+) (Ca(v)) channels play fundamental roles in the nervous system, but little is known about when or how their unique properties and cellular roles evolved. Of the three types of metazoan Ca(v) channels, Ca(v)1 (L-type), Ca(v)2 (P/Q-, N- and R-type) and Ca(v)3 (T-type),...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Gen Physiol
Κύριοι συγγραφείς: Smith, Carolyn L., Abdallah, Salsabil, Wong, Yuen Yan, Le, Phuong, Harracksingh, Alicia N., Artinian, Liana, Tamvacakis, Arianna N., Rehder, Vincent, Reese, Thomas S., Senatore, Adriano
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The Rockefeller University Press 2017
Θέματα:
Research Articles
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379919/
https://ncbi.nlm.nih.gov/pubmed/28330839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201611683
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