Sensitive Simultaneous Quantitation of Testosterone and Estradiol in Serum by LC-MS/MS without Derivatization and Comparison with the CDC HoSt Program

BACKGROUND: Very sensitive measurements of serum estrogens and testosterone are important in adult and pediatric endocrinology and immunoassays are known to lack the required performance at very low levels. Our aim was to develop a sensitive HPLC-MS/MS assay for both estradiol (E(2)) and testosteron...

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Udgivet i:J Chromatogr B Analyt Technol Biomed Life Sci
Main Authors: Schofield, Ryan C., Mendu, Damodara R., Ramanathan, Lakshmi V., Pessin, Melissa S., Carlow, Dean C.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379634/
https://ncbi.nlm.nih.gov/pubmed/28222335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2017.02.006
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