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Anxiolytic-like effects observed in rats exposed to the elevated zero-maze following treatment with 5-HT(2)/5-HT(3)/5-HT(4) ligands

The present study examined the effects of administering selective 5-HT antagonists and agonists to rats tested in the elevated zero-maze (EZM) model of anxiety. The EZM paradigm has advantages over the elevated plus-maze (EPM) paradigm with respect to measuring anxiety, yet has been utilized less fr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bell, Rob, Duke, Aaron A., Gilmore, Paula E., Page, Deaglan, Bègue, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379192/
https://ncbi.nlm.nih.gov/pubmed/24457553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03881
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