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Comparison of the elevated plus and elevated zero mazes in treated and untreated male Sprague-Dawley rats: Effects of anxiolytic and anxiogenic agents

The elevated plus and zero mazes (Plus and Zero, respectively) are used to assess behavior related to anxiety in rodents but direct comparisons of the two tests are lacking for rats. We compared the two methods in adult male Sprague-Dawley rats. Untreated rats in the Zero spent more time in open zon...

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Autors principals: Braun, Amanda A., Skelton, Matthew R., Vorhees, Charles V., Williams, Michael T.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006066/
https://ncbi.nlm.nih.gov/pubmed/20869983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2010.09.013
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