Specific mutations in KRAS codon 12 are associated with worse overall survival in patients with advanced and recurrent colorectal cancer

BACKGROUND: Activating mutations in KRAS have been suggested as potential predictive and prognostic biomarkers. However, the prognostic impact of specific point mutations remains less clear. This study assessed the prognostic impact of specific KRAS mutations on survival for patients with colorectal...

Full description

Saved in:
Bibliographic Details
Published in:Br J Cancer
Main Authors: Jones, Robert P, Sutton, Paul A, Evans, Jonathan P, Clifford, Rachel, McAvoy, Andrew, Lewis, James, Rousseau, Abigail, Mountford, Roger, McWhirter, Derek, Malik, Hassan Z
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
Subjects:
Molecular Diagnostics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379149/
https://ncbi.nlm.nih.gov/pubmed/28208157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.37
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items