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Leader cells regulate collective cell migration via Rac activation in the downstream signaling of integrin β1 and PI3K
Collective cell migration plays a crucial role in several biological processes, such as embryonic development, wound healing, and cancer metastasis. Here, we focused on collectively migrating Madin-Darby Canine Kidney (MDCK) epithelial cells that follow a leader cell on a collagen gel to clarify the...
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| Gepubliceerd in: | Sci Rep |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5379035/ https://ncbi.nlm.nih.gov/pubmed/25563751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07656 |
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