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Structure and function of the Zika virus full-length NS5 protein

The recent outbreak of Zika virus (ZIKV) has infected over 1 million people in over 30 countries. ZIKV replicates its RNA genome using virally encoded replication proteins. Nonstructural protein 5 (NS5) contains a methyltransferase for RNA capping and a polymerase for viral RNA synthesis. Here we re...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zhao, Baoyu, Yi, Guanghui, Du, Fenglei, Chuang, Yin-Chih, Vaughan, Robert C., Sankaran, Banumathi, Kao, C. Cheng, Li, Pingwei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378950/
https://ncbi.nlm.nih.gov/pubmed/28345656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14762
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