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Over expression of hRad9 protein correlates with reduced chemosensitivity in breast cancer with administration of neoadjuvant chemotherapy

Human Rad 9 (hRad9), part of the Rad9-Hus1-Rad1 complex plays an important role in DNA damage repair as an up-stream regulator of checkpoint signaling, however little is known about its role in response to chemotherapy of breast cancer and whether hRad9 inhibition can potentiate the cytotoxic effect...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Rep
मुख्य लेखकों: Yun, Haiqin, Shi, Ranran, Yang, Qingrui, Zhang, Xiaofang, Wang, Yan, Zhou, Xingchen, Mu, Kun
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378947/
https://ncbi.nlm.nih.gov/pubmed/25520248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07548
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