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Noncompetitive Inhibition of 5-HT(3) Receptors by Citral, Linalool, and Eucalyptol Revealed by Nonlinear Mixed-Effects Modeling

Citral, eucalyptol, and linalool are widely used as flavorings, fragrances, and cosmetics. Here, we examined their effects on electrophysiological and binding properties of human 5-HT(3) receptors expressed in Xenopus oocytes and human embryonic kidney 293 cells, respectively. Data were analyzed usi...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Jarvis, Gavin E., Barbosa, Roseli, Thompson, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378937/
https://ncbi.nlm.nih.gov/pubmed/26669427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.230011
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