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Paraquat toxicity is increased in Escherichia coli defective in the synthesis of polyamines.

We have shown that toxicity of paraquat for Escherichia coli is increased over 10-fold in strains defective in the biosynthesis of spermidine compared to isogenic strains containing spermidine. The increased sensitivity of these spermidine-deficient mutants to paraquat is eliminated by growth in med...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Minton, K W, Tabor, H, Tabor, C W
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53789/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2181453/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.7.2851
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