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In vivo mechanism-based inactivation of S-adenosylmethionine decarboxylases from Escherichia coli, Salmonella typhimurium, and Saccharomyces cerevisiae

S-adenosylmethionine decarboxylase (AdoMetDC), a key enzyme in the biosynthesis of spermidine and spermine, is first synthesized as a proenzyme, which is cleaved posttranslationally to form α and β subunits. The α subunit contains a covalently bound pyruvoyl group derived from serine that is essenti...

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Hlavní autoři: Li, Yong-Fu, Hess, Sonja, Pannell, Lewis K., Tabor, Celia White, Tabor, Herbert
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC58508/
https://ncbi.nlm.nih.gov/pubmed/11526206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.181341198
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