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Dysregulation of RNA Binding Protein Aggregation in Neurodegenerative Disorders

The unique biology of RNA binding proteins is altering our view of the genesis of protein misfolding diseases. These proteins use aggregation of low complexity domains (LCDs) as a means to regulate the localization and utilization of RNA by forming RNA granules, such as stress granules, transport gr...

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Bibliographische Detailangaben
Veröffentlicht in:Front Mol Neurosci
Hauptverfasser: Maziuk, Brandon, Ballance, Heather I., Wolozin, Benjamin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378767/
https://ncbi.nlm.nih.gov/pubmed/28420962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00089
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