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Degree of methylation burden is determined by the exposure period to carcinogenic factors

Aberrant DNA methylation accumulated in normal tissues, namely methylation burden, is associated with risk of carcinogenesis. The levels of methylation burden are known to be influenced by multiple factors, such as genetic factors and strengths of carcinogenic factors. However, the impact of the deg...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Takeshima, Hideyuki, Niwa, Tohru, Toyoda, Takeshi, Wakabayashi, Mika, Yamashita, Satoshi, Ushijima, Toshikazu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378290/
https://ncbi.nlm.nih.gov/pubmed/27992956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13136
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