Targeting MUC1 and JNK by RNA interference and inhibitor inhibit the development of hepatocellular carcinoma

Mucin 1 (MUC1), as an oncogene, is overexpressed in hepatocellular carcinoma (HCC) cells and promotes the progression and tumorigenesis of HCC through JNK/TGF‐β signaling pathway. In the present study, RNA interference (RNAi) and JNK inhibitor SP600125, which target MUC1 and/or JNK, were used to tre...

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Vydáno v:Cancer Sci
Hlavní autoři: Wang, Juan, Ni, Wei‐hua, Hu, Ke‐bang, Zhai, Xiao‐yu, Xie, Fei, Jie, Jing, Zhang, Nan‐nan, Jiang, Li‐na, Yuan, Hong‐yan, Tai, Gui‐xiang
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378288/
https://ncbi.nlm.nih.gov/pubmed/28012230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13144
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