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Targeting MUC1 and JNK by RNA interference and inhibitor inhibit the development of hepatocellular carcinoma
Mucin 1 (MUC1), as an oncogene, is overexpressed in hepatocellular carcinoma (HCC) cells and promotes the progression and tumorigenesis of HCC through JNK/TGF‐β signaling pathway. In the present study, RNA interference (RNAi) and JNK inhibitor SP600125, which target MUC1 and/or JNK, were used to tre...
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| Publicado no: | Cancer Sci |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5378288/ https://ncbi.nlm.nih.gov/pubmed/28012230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13144 |
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