Crucial role of carbonic anhydrase IX in tumorigenicity of xenotransplanted adult T‐cell leukemia‐derived cells

Carbonic anhydrase IX (CA9) is a membrane‐associated carbonic anhydrase that regulates cellular pH, is upregulated in various solid tumors, and is considered to be a therapeutic target. Here, we describe the essential role of CA9 in the tumorigenicity of cells derived from human adult T‐cell leukemi...

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Veröffentlicht in:Cancer Sci
Hauptverfasser: Nasu, Kentaro, Yamaguchi, Kazunori, Takanashi, Tomoka, Tamai, Keiichi, Sato, Ikuro, Ine, Shoji, Sasaki, Osamu, Satoh, Kennichi, Tanaka, Nobuyuki, Tanaka, Yuetsu, Fukushima, Takuya, Harigae, Hideo, Sugamura, Kazuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378273/
https://ncbi.nlm.nih.gov/pubmed/28075522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13163
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