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Network-based proteomic approaches reveal the neurodegenerative, neuroprotective and pain-related mechanisms involved after retrograde axonal damage

Neurodegenerative processes are preceded by neuronal dysfunction and synaptic disconnection. Disconnection between spinal motoneuron (MN) soma and synaptic target leads either to a retrograde degenerative process or to a regenerative reaction, depending injury proximity among other factors. Distingu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Casas, Caty, Isus, Laura, Herrando-Grabulosa, Mireia, Mancuso, Francesco M., Borrás, Eva, Sabidó, Eduardo, Forés, Joaquim, Aloy, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378195/
https://ncbi.nlm.nih.gov/pubmed/25784190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09185
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