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Low intensity ultrasound mediated liposomal doxorubicin delivery using polymer microbubbles

Cardiotoxicity is the major dose-limiting factor in the chemotherapeutic use of doxorubicin (Dox). A delivery vehicle that can be triggered to release its payload in the tumoral microvasculature but not in healthy tissue would help improve the therapeutic window of the drug. Delivery strategies comb...

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Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: Yu, Francois T.H., Chen, Xucai, Wang, Jianjun, Qin, Bin, Villanueva, Flordeliza S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378154/
https://ncbi.nlm.nih.gov/pubmed/26567985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.5b00421
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