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Low intensity ultrasound mediated liposomal doxorubicin delivery using polymer microbubbles

Cardiotoxicity is the major dose-limiting factor in the chemotherapeutic use of doxorubicin (Dox). A delivery vehicle that can be triggered to release its payload in the tumoral microvasculature but not in healthy tissue would help improve the therapeutic window of the drug. Delivery strategies comb...

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Dettagli Bibliografici
Pubblicato in:Mol Pharm
Autori principali: Yu, Francois T.H., Chen, Xucai, Wang, Jianjun, Qin, Bin, Villanueva, Flordeliza S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378154/
https://ncbi.nlm.nih.gov/pubmed/26567985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.5b00421
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