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Mitochondrial Replacement Therapy: Are Mito-nuclear Interactions Likely To Be a Problem?

It has been suggested that deleterious interactions between the mitochondrial and nuclear genomes could pose a problem for mitochondrial replacement therapy (MRT). This is because the mitochondrial genome is placed in a novel nuclear environment using this technique. In contrast, it is inherited wit...

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Detalhes bibliográficos
Publicado no:Genetics
Autor principal: Eyre-Walker, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378100/
https://ncbi.nlm.nih.gov/pubmed/28360127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.196436
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