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MicroRNA-375 Is Induced in Cisplatin Nephrotoxicity to Repress Hepatocyte Nuclear Factor 1-β

Nephrotoxicity is a major adverse effect of cisplatin-mediated chemotherapy in cancer patients. The pathogenesis of cisplatin-induced nephrotoxicity remains largely unclear, making it difficult to design effective renoprotective approaches. Here, we have examined the role of microRNAs (miRNAs) in ci...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Hao, Jielu, Lou, Qiang, Wei, Qingqing, Mei, Shuqin, Li, Lin, Wu, Guangyu, Mi, Qing-Sheng, Mei, Changlin, Dong, Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377773/
https://ncbi.nlm.nih.gov/pubmed/28119452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.754929
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