CD44 Transmembrane Receptor and Hyaluronan Regulate Adult Hippocampal Neural Stem Cell Quiescence and Differentiation

Adult neurogenesis in the hippocampal subgranular zone (SGZ) is involved in learning and memory throughout life but declines with aging. Mice lacking the CD44 transmembrane receptor for the glycosaminoglycan hyaluronan (HA) demonstrate a number of neurological disturbances including hippocampal memo...

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發表在:J Biol Chem
Main Authors: Su, Weiping, Foster, Scott C., Xing, Rubing, Feistel, Kerstin, Olsen, Reid H. J., Acevedo, Summer F., Raber, Jacob, Sherman, Larry S.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2017
主題:
Neurobiology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377763/
https://ncbi.nlm.nih.gov/pubmed/28154169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.774109
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