Hyaluronan Anchored to Activated CD44 on Central Nervous System Vascular Endothelial Cells Promotes Lymphocyte Extravasation in Experimental Autoimmune Encephalomyelitis

The extravasation of lymphocytes across central nervous system (CNS) vascular endothelium is a key step in inflammatory demyelinating diseases including multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE). The glycosaminoglycan hyaluronan (HA) and its receptor, CD44, have bee...

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Detalhes bibliográficos
Main Authors: Winkler, Clayton W., Foster, Scott C., Matsumoto, Steven G., Preston, Marnie A., Xing, Rubing, Bebo, Bruce F., Banine, Fatima, Berny-Lang, Michelle A., Itakura, Asako, McCarty, Owen J. T., Sherman, Larry S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460429/
https://ncbi.nlm.nih.gov/pubmed/22865853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.356287
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