Elevated serum 1,25(OH)(2)-vitamin D(3) level attenuates renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction in kl/kl mice

Previous studies have suggested that Klotho provides reno-protection against unilateral ureteral obstruction (UUO)-induced renal tubulointerstitial fibrosis (RTF). Because the existing studies are mainly performed using heterozygous Klotho mutant (HT) mice, we focused on the effect of UUO on homozyg...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sun, Yujing, Zhou, Gengyin, Gui, Ting, Shimokado, Aiko, Nakanishi, Masako, Oikawa, Kosuke, Sato, Fuyuki, Muragaki, Yasuteru
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377451/
https://ncbi.nlm.nih.gov/pubmed/25297969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06563
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