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Exposure of Heligmosomoides polygyrus and Trichuris muris to albendazole, albendazole sulfoxide, mebendazole and oxantel pamoate in vitro and in vivo to elucidate the pathway of drug entry into these gastrointestinal nematodes

Millions of people are treated with anthelmintics to control soil-transmitted helminth infections; yet, drug distribution in the plasma and gastrointestinal tract compartments and the pathway of drug uptake into gastrointestinal nematodes responsible for the pharmacological effect are unknown. We as...

詳細記述

保存先:
書誌詳細
出版年:Int J Parasitol Drugs Drug Resist
主要な著者: Cowan, Noemi, Meier, Charles, Neodo, Anna, Keiser, Jennifer
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377441/
https://ncbi.nlm.nih.gov/pubmed/28371660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2017.03.005
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