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Exposure of Heligmosomoides polygyrus and Trichuris muris to albendazole, albendazole sulfoxide, mebendazole and oxantel pamoate in vitro and in vivo to elucidate the pathway of drug entry into these gastrointestinal nematodes

Millions of people are treated with anthelmintics to control soil-transmitted helminth infections; yet, drug distribution in the plasma and gastrointestinal tract compartments and the pathway of drug uptake into gastrointestinal nematodes responsible for the pharmacological effect are unknown. We as...

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Pubblicato in:Int J Parasitol Drugs Drug Resist
Autori principali: Cowan, Noemi, Meier, Charles, Neodo, Anna, Keiser, Jennifer
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377441/
https://ncbi.nlm.nih.gov/pubmed/28371660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2017.03.005
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