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AZD0530 sensitizes drug‐resistant ALK‐positive lung cancer cells by inhibiting SRC signaling

Most tumors develop resistance to targeted cancer drugs, even though these drugs have produced substantial clinical responses. Here we established anaplastic lymphoma kinase (ALK)‐positive drug‐resistant lung cancer cell lines, which are resistant to ceritinib (LDK378). We found that ceritinib treat...

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Podrobná bibliografie
Vydáno v:FEBS Open Bio
Hlavní autoři: Zhao, Yi, Yang, Yi, Xu, Yunhua, Lu, Shun, Jian, Hong
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377386/
https://ncbi.nlm.nih.gov/pubmed/28396832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12162
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