Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells.

We have used polyclonal anti-synthetic peptide serum to study the role of retinoblastoma gene (RB) inactivation in a variety of human tumor cell lines. Our analysis indicates that inactivation of the RB protein, p105-Rb, is universal in retinoblastoma cells, vindicating the predictions of the Knudso...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Horowitz, J M, Park, S H, Bogenmann, E, Cheng, J C, Yandell, D W, Kaye, F J, Minna, J D, Dryja, T P, Weinberg, R A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1990
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53773/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2181449/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.7.2775
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!