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The crystal structure of Zika virus NS5 reveals conserved drug targets

Zika virus (ZIKV) has emerged as major health concern, as ZIKV infection has been shown to be associated with microcephaly, severe neurological disease and possibly male sterility. As the largest protein component within the ZIKV replication complex, NS5 plays key roles in the life cycle and surviva...

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Библиографические подробности
Опубликовано в: :EMBO J
Главные авторы: Duan, Wenqian, Song, Hao, Wang, Haiyuan, Chai, Yan, Su, Chao, Qi, Jianxun, Shi, Yi, Gao, George F
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376968/
https://ncbi.nlm.nih.gov/pubmed/28254839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201696241
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