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Identification of Rare PB2-D701N Mutation from a Patient with Severe Influenza: Contribution of the PB2-D701N Mutation to the Pathogenicity of Human Influenza

Several amino acid changes have been previously implicated in adaptation of avian influenza viruses to human hosts, among them the D701N change in the PB2 polymerase subunit that also is the main determinant of avian virus pathogenesis in animal models. However, previous studies using recombinant vi...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Front Microbiol
Κύριοι συγγραφείς: Nieto, Amelia, Pozo, Francisco, Vidal-García, Matxalen, Omeñaca, Manuel, Casas, Inmaculada, Falcón, Ana
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Frontiers Media S.A. 2017
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376584/
https://ncbi.nlm.nih.gov/pubmed/28421062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00575
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