In vivo MRI and ex vivo histological assessment of the cardioprotection induced by ischemic preconditioning, postconditioning and remote conditioning in a closed-chest porcine model of reperfused acute myocardial infarction: importance of microvasculature

BACKGROUND: Cardioprotective value of ischemic post- (IPostC), remote (RIC) conditioning in acute myocardial infarction (AMI) is unclear in clinical trials. To evaluate cardioprotection, most translational animal studies and clinical trials utilize necrotic tissue referred to the area at risk (AAR)...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Transl Med
Main Authors: Baranyai, Tamás, Giricz, Zoltán, Varga, Zoltán V., Koncsos, Gábor, Lukovic, Dominika, Makkos, András, Sárközy, Márta, Pávó, Noémi, Jakab, András, Czimbalmos, Csilla, Vágó, Hajnalka, Ruzsa, Zoltán, Tóth, Levente, Garamvölgyi, Rita, Merkely, Béla, Schulz, Rainer, Gyöngyösi, Mariann, Ferdinandy, Péter
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376486/
https://ncbi.nlm.nih.gov/pubmed/28364777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1166-z
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