In vivo MRI and ex vivo histological assessment of the cardioprotection induced by ischemic preconditioning, postconditioning and remote conditioning in a closed-chest porcine model of reperfused acute myocardial infarction: importance of microvasculature

BACKGROUND: Cardioprotective value of ischemic post- (IPostC), remote (RIC) conditioning in acute myocardial infarction (AMI) is unclear in clinical trials. To evaluate cardioprotection, most translational animal studies and clinical trials utilize necrotic tissue referred to the area at risk (AAR)...

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Detalhes bibliográficos
Publicado no:J Transl Med
Principais autores: Baranyai, Tamás, Giricz, Zoltán, Varga, Zoltán V., Koncsos, Gábor, Lukovic, Dominika, Makkos, András, Sárközy, Márta, Pávó, Noémi, Jakab, András, Czimbalmos, Csilla, Vágó, Hajnalka, Ruzsa, Zoltán, Tóth, Levente, Garamvölgyi, Rita, Merkely, Béla, Schulz, Rainer, Gyöngyösi, Mariann, Ferdinandy, Péter
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376486/
https://ncbi.nlm.nih.gov/pubmed/28364777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1166-z
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