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Aspirin-triggered resolvin D1 attenuates PDGF-induced vascular smooth muscle cell migration via the cyclic adenosine monophosphate/protein kinase A (cAMP/PKA) pathway

BACKGROUND AND OBJECTIVES: Resolvin D1 (RvD1) is a specialized pro-resolving lipid mediator that has been previously shown to attenuate vascular smooth muscle cell (VSMC) migration, a key process in the development of intimal hyperplasia. We sought to investigate the role of the cAMP/PKA pathway in...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mottola, Giorgio, Chatterjee, Anuran, Wu, Bian, Chen, Mian, Conte, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376330/
https://ncbi.nlm.nih.gov/pubmed/28362840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174936
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