Adrenergic Receptors in Individual Ventricular Myocytes: The Beta-1 and Alpha-1B Are in All Cells, the Alpha-1A Is in a Subpopulation, and the Beta-2 and Beta-3 Are Mostly Absent

RATIONALE: It is unknown if every ventricular myocyte expresses all 5 of the cardiac adrenergic receptors (ARs), beta-1, beta-2, beta-3, alpha-1A, and alpha-1B. The beta-1 and beta-2 are thought to be the dominant myocyte ARs. OBJECTIVE: Quantify the 5 cardiac ARs in individual ventricular myocytes....

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Pubblicato in:Circ Res
Autori principali: Myagmar, Bat-Erdene, Flynn, James M., Cowley, Patrick M., Swigart, Philip M., Montgomery, Megan D., Thai, Kevin, Nair, Divya, Gupta, Rumita, Hosoda, Chihiro, Melov, Simon, Baker, Anthony J., Simpson, Paul C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376223/
https://ncbi.nlm.nih.gov/pubmed/28219977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.310520
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