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Mitochondrial superoxide in osteocytes perturbs canalicular networks in the setting of age-related osteoporosis

Osteocytes are major bone cells that play a crucial role in maintaining the quality of and healing damage to bone tissue. The number of living osteocytes and canalicular networks declines in an age-dependent manner. However, the pathological effects of mitochondrial redox imbalances on osteocytes an...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kobayashi, Keiji, Nojiri, Hidetoshi, Saita, Yoshitomo, Morikawa, Daichi, Ozawa, Yusuke, Watanabe, Kenji, Koike, Masato, Asou, Yoshinori, Shirasawa, Takuji, Yokote, Koutaro, Kaneko, Kazuo, Shimizu, Takahiko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376208/
https://ncbi.nlm.nih.gov/pubmed/25779629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09148
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